LEV S.TSIMRING

Address: Synthetic Biology Institute University of California, San Diego La Jolla, CA 92093-0328 (858) 534-0816 FAX (858) 534-1892 E-mail: ltsimring 'at' ucsd.edu http://synbio.ucsd.edu/lev

Education: B. S. Physics, Gorky State University, Gorky, USSR, 1980 Ph.D. Physics, Institute of Oceanology, Moscow, USSR, 1986

POSITIONS:

2022 - present: Associate Director, Synthetic Biology Institute, University of California, San Diego

2009 - present: Research Scientist, Synthetic Biology Institute, University of California, San Diego

2010 - 2022: Associate Director, BiocCircuits Institute, University of California, San Diego

2009 - 2022: Research Scientist, BioCircuits Institute, University of California, San Diego

1998 - 2009: Research Physicist, Institute for Nonlinear Science, University of California, San Diego

1999 - 2009: Associate Director, Institute for Nonlinear Science, University of California, San Diego

1996 - 1998: Associate Research Physicist, Institute for Nonlinear Science, University of California, San Diego

1992 - 1996: Assistant Research Physicist, Institute for Nonlinear Science, University of California, San Diego

1980 - 1991: Research Assistant, Research Scientist, Senior Research Scientist, Institute of Applied Physics, USSR Academy of Sciences, Gorky, USSR

1988 - 1991: Senior lecturer, Radiophysics Department, Gorky State University, Gorky, USSR

OTHER:

Fellow, American Physical Society, 2011

Member of Editorial boards (current): Physical Review Letters; Nonlinearity; PLoS ONE; Bulletin of Mathematical Biology; Chaos, Solitons, and Fractals

Director, Mathematical Modeling Core, San Diego Center for Systems Biology, 2010 -2018

Co-Principal Investigator, Systems Biodynamics Lab, Bioengineering Department, UCSD, 2004-present

Guest editor: New Journal of Physics (2014)

Referee for Nature; Nature Communications; Science; Science Advances; Physical Review Letters; The Physical Review E; Europhysics Letters; Biophysical Journal; Physical Biology; Proceedings of the National Academy of Sciences USA; Journal of Statistical Physics; Cell Systems; Chaos; Nonlinearity; Journal of Fluid Mechanics; PLoS Computational Biology; PLoS ONE; New Journal of Physics; Physical D; Physics Letters A; ACS Synthetic Biology and others

Ad-hoc reviewer for NIH panels, 2015, 2016

Organizer, Summer schools on quantitative biology, San Diego, 2012-2017

Organizer, Annual Winter q-bio meetings, Hawaii, 2013-2018

Organizer and Chair, focus session at the American Physical Society March meeting, Boston, March 2012

Organizer, "Living Nonlinear Dynamics", International conference, San Diego, April 21-23, 2011

Co-chair, Gordon Research Conference on Granular Flows, 2002

Co-organizer, Winter School "Perspectives of Nonlinear Dynamics," San Diego, January 2012

Organizer, Annual Winter Schools on Communications with Chaos, San Diego, 1999-2003

Member of Organizing Committee, Winter Schools on Nonlinear Waves, Gorky, 1985,1987,1989

Member of Organizing Committee, Fall Schools on Methods for Hydrophysical Research, 1988, 1990

Visiting Professor, University of Marseille, France, June, September 2007, June 2009.

Visiting Scientist, Max Planck Insitute for Complex Systems, Dresden, Germany, June-July 1999.

Visiting Scientist, Bar-Ilan University, Tel-Aviv, Israel, May-June, 1994

Visiting Scientist, Royal Netherlands Meteorological Institute, Utrecht, Netherlands, May - June, 1991

Visiting Scientist, Institute for Coastal Hydrodynamics, Gdansk, Poland, January, 1989, July, 1989

PUBLICATIONS:

4 monographs (co-authored or co-edited) and more than 180 peer-reviewed papers in leading scientific journals including: Nature; Science; Proceedings of the National Academy of Sciences USA; Reviews of Modern Physics; Physical Review Letters; Physical Review A,B,E; New Journal of Physics; Reports on Preogress in Physics, Biophysical Journal; Physcal Biology; Molecular Systems Biology; Genetics; PLoS Computational Biology; PLoS ONE; Journal of Statistical Physics, Europhysics Letters; Physics Letters A; IEEE Transactions on Circuits and Systems; Journal of Fluid Mechanics; Physica A,D; Chaos; Bioinformatics; ACS Synthetic Biology, etc.

ISI citation index: 11000+; h-index: 50
Google Scholar citation index: 19300+; h-index: 64

RESEARCH GRANTS:

NSF grant "Model-driven bacterial engineering for complex spheroid environments"; 2020 - present (Co-PI)

NIH RO1 grant "Design and characterization of bacterial population dynamics in solid tumor models"; 2020 - present (Co-PI)

NIH RO1 grant "Network-Driven Dynamics of Replicative Aging"; 2017 - present (Co-PI)

NIH RO1 grant "Engineered Gene Circuits for Basic Science and Biotechnology"; 2004 - present (Co-PI)

ONR grant "Distributed spatiotemporal dynamics of synthetic gene circuits" 2016 - 2018 (PI)

NSF-NIH MPI grant "Adaptive Queueing in Intracellular Networks"; 2015 - 2018 (PI)

NIH P50 grant "San Diego Center for Systems Biology (SDCSB) for cellular stress responses"; 2010 - 2019 (Co-Investigator)

NIH RO1 grant "Delays and variability in single-cell NFkB signaling"; 2010 - 2015 (PI)

ARO/MURI grant "Dynamic Artificial Cells Composed of Synthetic Bioorthogonal Membranes"; 2014 - present (Co-Investigator)

NIH RO1 grant "Metabolic control in a dynamic environment"; 2007 - 2011 (Co-Investigator)

ONR/MURI grant "Chemical Discrimination and Localization using Biologically Based Olfactory Processing"; 2007 - 2010 (Co-Investigator)

Department of Energy, Office of Basic Energy Sciences grant "Modeling for Process Control: High-Dimensional Systems"; 1995 - 2006 (PI)

NSF grant "QSB: The Design and Construction of Coupled Genetic Regulatory Modules", 2003 - 2006 (Co-PI)

Department of Energy, Office of Basic Energy Sciences grant "Spatiotemporal Wave Patterns: Models and Analysis"; 1996 - 2005 (Co-PI)

NATO Collaborative Linkage Grant "Information dynamics of complex networks"; 2002 - 2003 (PI)

Department of the Army, Army Research Office, Multidisciplinary University Research Initiative (MURI) "Digital Communication Devices Based on Nonlinear Dynamics and Chaos"; 1998 - 2003 (co-PI)

UC-MEXUS CONACYT, "Research and Development of Novel Methods for Controlling Nonlinear Dynamics and its Applications"; 2000 - 2002 (US PI)

Electric Power Research Institute (EPRI), for "Process Validation and Control: Nonlinear Modeling" (PI); February, 1996 - 1998

INVITED SPEAKER AT:

IUTAM Symposium "Nonlinear Deformation Waves", Tallin, Estonia, May, 1982

International Conference "Nonlinear and Turbulent Processes in Physics", Kiev, Ukraine, October, 1987

Euromech Colloquium #241 "Nonlinear Waves in Active Media", Tallinn, Estonia, May, 1988

5-th Liquid State Conference on Turbulence of the European Physical Society, Moscow, USSR, October, 1989

International Workshop "Nonlinear World", Kiev, Ukraine, October, 1989

XV EGS General Assembly, Copenhagen, Denmark, April, 1990

Fall School "Methods for Hydrophysical Research", Kaliningrad, USSR, September, 1990

XVI EGS General Assembly, Wiesbaden, Germany, April, 1991

International Workshop "Nonlinear Water Waves", Bristol, England, October, 1991

NSF-CBMS Conference "Weak Turbulence and Nonlinear Waves", Clevelend, Ohio, May, 1992

International Workshop "Spatially Extended Nonequilibrium Media", Santa Barbara, California, July, 1992

UCSD/Nizhni Novgorod Nonlinear Science School, San Diego, California, January 1993.

NATO Advanced Research Workshop "Spatio-Temporal Patterns in Nonequilibrium Complex Patterns", Santa Fe, New Mexico, April 1993.

FSU-USA Chaos conference, Woods Hole, Massachusetts, July 1993.

2-nd Experimental Chaos Conference, Washington D.C., October 1993.

Technion, Haifa, Israel, June 1994.

Weizmann Institute of Science, Rehovot, Israel, June 1994.

Physics Department Colloquium, California State University, Long Beach, October, 1994

Istituto Nazionale di Ottica, Florence, Italy, April, 1995

Institut Non-Lineaire de Nice, France, April, 1995

SIAM Conference on Dynamical Systems, Snowbird, Utah, May, 1995

Weizmann Institute of Science, Rehovot, Israel, April 1996

V International Bar-Ilan Conference "Frontiers of Condensed Matter Physics", Israel, April 1997

Complex Systems Seminar, UCSD, May 1997

UNED, Madrid, Spain, May 1997

SIAM Conference on Dynamical Systems, Snowbird, Utah, May 1997

SPIE Annual Meeting, San Diego, CA, July 1997

Center for Nonlinear Dynamics, University of Texas, Austin, November 15, 1997

Applied Mathematics Colloquium, University of Colorado, Boulder, February 1998.

Workshop "Theory of Granular Materials", Argonne National Lab, April 1998.

Energy Sciences Conference, Argonne National Lab, May 1998.

Workshop on Physics of Granular Matter, Pisa, Italy, October 1998.

AMS Fall Western Sectional Meeting, Tucson, AZ, November 1998.

Physics Colloquium, San Diego State University, November 1998.

Oak Ridge National Labortory, March 1999.

Workshop on Defects in Nonequilibrium Media, Dresden, Germany, July 1999.

Workshop on combustion "Flameday-1999", Rome, Italy, November 1999.

DOE BES Workshop "Complex Interactions in Granular Materials", Argonne National Laboratory, April 7-8, 2000.

Centro de Investigaciones en Optica, Leon, Mexico, September 19, 2000.

Instituto Nazionale di Ottica, Florence, Italy, October 23, 2000

NOLTA-2001, Miyagi-Zao, Japan, Oct.27-Nov.1, 2001

Northwestern University, Evanston, March 15, 2002

NATO - Advanced Research Workshop "Stochastic Systems: From Randomness to Complexity", Erice, Italy, July 27 - August 1, 2002

Workshop "Formation of Structures in Granular Matter", Lorentz Center, Leiden, Netherlands, August 19-30, 2002

Center for Nonlinear Dynamics, Georgia Tech, October 25, 2002.

MEDYFINOL-02, Colonia del Sacramento, Uruguay, December 2002.

Second Workshop on Granular Flow and Kinetics, Argonne, January, 2003.

NATO Advanced Study Institute "PhysBio: Non-equilibrium in Physics and in Biology", Benasque, Spain, August 2003.

International Symposium "Topical Problems in Nonlinear Wave Physics", Nizhni Novgorod - Moscow, Russia, September 2003.

UCLA, Physics Department, 15 October 2003.

Southern Workshop on Granular Materials, Pucon, Chile, December 2003

Workshop "Stochastic systems with delay and memory", Wittenberg, Germany, 2-5 February 2004.

Winter school "Nonlinear Waves - 2004", Nizhni Novgorod, Russia, March 2004.

Pan-American Advanced Studies Institute (PASI) on Modern Challenges in Statistical Mechanics II, Albuquerque, New Mexico, March 2004.

Chemical Engineering Seminar, UCSB, Santa Barbara, June 3, 2004.

SIAM Conference on Life Sciences, Portland, Oregon, July 11-14, 2004.

Workshop "Transport and Self-Organization in Complex Systems", Porto Alegre, Brazil, August 8-12, 2004

Workshop "Fundamentals of Self-Assembly in Complex Materials: Self-organization and Continuum Models", Argonne National Lab, Argonne, August 25-26, 2004.

APS March meeting, Los Angeles, March 21-25, 2005

SIAM conference on Applications of Dynamical Systems, Snowbird, Utah, May 2005

3rd SPIE International Symposium on Fluctuations and Noise, Austin, Texas, May 2005

Dynamics Days Europe, Berlin, July 25-28, 2005

Workshop "Pattern formation and Transport Phenomena", Joao Pessoa, Brazil, August 5-12, 2005

6th Crimean School and Workshops "Nonlinear Dynamics, Chaos, and Applications", Mellas, Crimea, Ukraine, May 15-19, 2006

International seminar and workshop "Constructive Role of Noise in Complex Systems", Dresden, Germany, July 17-21, 2006

Racah Institute of Physics, Hebrew University of Jerusalem. Israel, November 22, 2006

APS March meeting, Denver, March 5-9, 2007

Spring School on Biological Networks, Les Houches, France, April, 9-20, 2007.

Workshop "Multiscale Modeling of Self-Organization in Active Biological Systems", Argonne National Laboratory, 28-30 April 2007

Workshop "Bifurcations and symmetries in Genetics and Neuroscience", CIRM Luminy, Marseilles, June 11-12, 2007.

IMA Workshop "Organization of Biological Networks", Minneapolis, March 3-7, 2008.

Workshop "Chaos and Dynamics in Biological Networks", Cargese, Corsica, May 3-10, 2008.

IMA Workshop "Stochastic modeling of Intracellular Networks", Minneapolis, May 11-13, 2008.

Workshop "Self-organization and dynamics of active matter", Institut Henri Poincare, Paris, January 26-30, 2009.

SIAM Conference on Applications of Dynamical Systems, Snowbird, Utah, May 16-20, 2009.

SAM09, I2CAM "Soft Active Materials: From Granular Rods to Flocks, Cells and Tissues", Syracuse, NY, May 18-21, 2009.

University of Marseille, Marseille, June 2009.

XXXIX Winter Meeting on Statistical Physics, Taxco, Mexico, January 5-8, 2009

BIRS Workshop "Multi-scale Stochastic Modeling of Cell Dynamics", Banff, Canada, January 17-22, 2010

International conference "Nonlinear Dynamics: New Directions", Guanajuato, Mexico, May 11-14, 2010

Yale University, Physics seminar, August 24, 2010

Chronobiology Workshop, San Diego, November 8, 2010

MBI Workshop "Dynamical Systems in Biosciences", Columbus, OH, March 21-25, 2011

Oakland University, Physics colloquium, April 14, 2011

Northwestern University, Applied Math colloquium, May 9, 2011

Workshop on "Collective Dynamics and Pattern Formation in Active Matter Systems", Dresden, Germany, September 12-16, 2011

XII Latin-American Workshop on Nonlinear Phenomena (LAWNP 2011), San Luis Potosi, Mexico, October 10-14, 2011

MBI Workshop "Stochastic Processes in Cell and Population Biology", Columbus, OH, October 23-28, 2011

Institute of Physics, Humboldt-University. Belin, Germany, February 21, 2012

3rd VW Status Symposium "New trends in simulating biological systems and soft matter", Potsdam, Germany, February 22-24, 2012

UNAM, Campus Morelos, Cuernavaca, Mexico, March 12, 2013.

University of Houston, Applied Math seminar, April 2013

Georgia Tech, Math seminar, April 2013

Workshop "Information, probability and inference in systems biology" (IPISB 2013), Edinburgh, July 2013

Center for Theoretical Biological Physics, UCSD seminar, October 14, 2013

APS March meeting, Denver, March 3-7, 2014

Young Scientist Symposium, IST, Vienna, May 2014

7th Chaotic Modeling and Simulation International Conference (CHAOS2014), Lisbon, Portugal, June 7-10, 2014

Dynamics Days, Houston, January 9-11, 2015

6th CCB Symposium: From Cells to Clinic, UCSD, February 26, 2015

3 invited lectures, UASLP, San Luis Potosi, Mexico, March 9-14, 2015

Universite Paris-Diderot, Paris, France, April 2015

Ecole Normale Superieure, Paris, France, April 7, 2015

Universite du Havre, Le Havre, France, April 9, 2015

2015 SIAM Conference on Applications of Dynamical Systems, Snowbird, Utah, May 17-21, 2015

8th International Conference on Engineering of Chemical Complexity, Garching/Munich, Germany, June 22-25 , 2015

IMA Workshop "Reflected Brownian Motions, Stochastic Networks, and their Applications" June 25-27, 2015

9th Summer q-bio school, Fort Collins, Colorado, July 8, 2015

Material Science Division, Argonne National Laboratory, January 7, 2016

International workshop "Collective Dynamics in Microorganisms and Cellular Systems", Sde Boker, Israel, May 22-25, 2016

International workshop "Advances in the collective behaviour of complex systems University of Potsdam, Germany, September 1-3, 2016

Max Planck Institute for Terrestrial Microbiology, Marburg, Germany, September 5, 2016

Gordon Research Conference "Stochastic Physics in Biology", Ventura, CA, January 8-13, 2017

BioPhys-2017 conference, Mexico City, May 17-20, 2017

Applied Math Colloquium, University of Arizona, Tucson, November 3, 2017

DPG/EPS Annual meeting, keynote talk. Berlin, Germany, March 12, 2018.

International Workshop "Predicting Transitions in Complex Systems", Dresden, Germany, April 23-27, 2018

EMBO/EMBL Symposium "Biological Oscillators: Design, Mechanism, Function", Heidelberg, Germany, June 3-5, 2018

Physics of Active Matter. Vina del Mar, Chile, July 15-17, 2019


August 2018