Biodynamics Lab

Dr. Jeff Hasty

Dr. Jeff Hasty

Paul A Libby Endowed Chair, Professor Jeff Hasty
Departments of Bioengineering and Molecular Biology
University of California San Diego


Research Overview

The Biodynamics Laboratory (BDL) seeks to understand the network interactions that mediate gene regulation and cellular signaling. Since behavior arising from these complex interactions is difficult to predict with qualitative reasoning, we employ experimentally validated computational modeling approaches. We design and construct de novo synthetic gene circuits, which provide a natural framework for reducing the complexity of gene regulatory networks. We use tools from physics and engineering to study such simplified systems and to dissect, analyze, and control the modular components that govern the dynamics of gene regulation and cellular signaling.